Dermatology research 2025
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Acne prevention and lifestyle tips and how to prevent acne naturally

Sleep and immune system,

The Role of Sleep in Acne Prevention and Immune Regulation

1. Sleep enough. We recommend 8 hours of sleep every night. A deep sound sleep is even more important than number of hours you sleep. During deep sleep, the production of growth hormone is at its peak. Growth hormone helps absorption of various essential nutrients such as amino acids into the cells and healing of tissues throughout your body. Insufficient sleep contribute to hormonal imbalance and production of more sebum resulting in aggravation of acne breakouts. Sleep is the best way by which body renew itself overnight and gets rid of stress.

This will boost your immune system to function more effectively in fighting against bacteria and involved inflammation. The hormone also stimulates your bone marrow, where your immune system cells are born. Another hormone produced during sleep is melatonin. This hormone inhibits tumors from growing, prevents viral infections, stimulates your immune system, increases antibodies in your saliva, has antioxidant properties and enhances the quality of sleep.

Diet, what food causes acne?

Clear Skin Nutrition: Dietary Modifications for Acne Prevention

2. Even though many studies regards role of diet in acne vulgaris as equivocal, a diet rich in fibers, fruits and nuts and low in glycemic index seem to be helpful in acne prevention and control. What precipitates acne when it comes to type of foods is not an straightforward answer, however, certain considerations certainly helpful in maintenance treatment of acne. Some studies indicate a link between dairy food and acne breakouts as they can illicit an inflammatory response in sebaceous units.

Excercise & relaxation techniques,

Exercise and Stress Reduction: Hormonal Equilibrium for Acne-Free Skin

3. Exercise regularly and, more importantly, take a shower after. Exercise can increase the circulation and oxygenation of your skin and fight free radical generation. It also promotes hormonal balance in your body. Hormonal disturbances are quite common in adult acne patients as androgens are massively involved in pathogensis of acne vulgaris and sebaceous glands are androgen sensitive. Acne prevention could be facilitated by any means, which bring hormonal balance to the body not only in hormonal acne but acne vulgaris in general. Thirty minutes, three times a week may be a minimum for an exercise program to be beneficial in your acne prevention routine.

4. Treat yourself with a 20-minutes relaxation everyday when you do not think of anything, just listen to the sounds around you, whatever they are and stop thinking about anything. Participation in Yoga or Tichi are among other methods for acne prevention. Relaxation can increase microcirculation of your skin and help your body to rid adult acne by bringing hormonal balance to your body. Low, moderate to high intensity exercises all are considered beneficial in maintenance treatment of acne.

Skin care to prevent acne

1. Any valuable and effective acne skin care regimen may be consisted of at least three elements.
a) a cleanser especially helps with acne prevention b) a moisturizer to keep skin hydrated and nourished with essential fatty acids to control increase in sebum production and acne prevention c) a treatment fortified with antioxidants such as acne serum to get rid of inflammatory acne lesions

Cleansing and skin sensitivities

2. Steam your face not more than once a week with hot water. You can infuse two teabag of Chamomile in the hot water. Do not do this more than once a week. This will help deep cleansing of your skin pores and elimination of fat debris

3. Do not use wash clothes to clean your skin. Do not scrub your face with anything other than cotton balls as they may irritate your skin. Note that acne prone skin is very sensitive to mechanical stimulation and touching your face places staphylococcus species namely, staphylococcus epidermidis, rampant on your hands and nails on your face.

Natural cleansers as opposed to soaps

4. If you cannot afford a good cleanser, wash your face with regular white vinegar. Use cotton balls to spread the vinegar on your skin and wash your face with water after a few minutes. Hippocrates acne prone cleanser is a therapeutic cleanser which prevents bacterial colonization in the skin while it maintains skin’s microbiome and prevents dysbiosis. It cleanses your skin while treating acne breakouts, soothing your skin and reducing its inflammation. This cleanser is hypoallergenic and suitable for most sensitive skin. It is of note that prevention from acne scars requires prompt treatment of acne so a good cleanser worth it more that what it sounds.

Acne prevention cream

5. Ensure use of a moisturizer for acne prone skin during the day while you are using treatments such as Retinoids or Salicylic acids at nights. Most treatments to prevent adult acne tend to get your skin dry. It is important to nourish your skin at the same time with a good moisturizer. Hippocrates acne prone Day Effect is a moisturizer engineered for acne prone skin to provide your skin with sufficient moisture and nutrients
Sebum regulating cream to prevent acne

Oily skin and bathing

6. Everyday cold/lukewarm showers are of crucial importance for acne prevention and control of oily skin. Taking showers sounds too simplistic, however, in time you be noticing how this simple exercise can aid your body to rid acne. Use a body wash or a shampoo instead of a soap. Soaps can overdry your skin, alter skin pH and stimulate sebaceous glands to produce more oils and may not be a good choice for acne prevention especially in case of sensitive skin.

Moisturize your skin after each shower. Finding a good moisturizer could be a challenge but use of a oil free moisturizer seems dubious as overproductive sebacious glands while they generate copious oils, grow depleted in essential skin lipids which should be replenished. Once a week try a hot bath. After washing your body, fill the bath tub with hot water and one cup of either Epsom salts or sea salt. You can add some foam bath to the water too. Stay in for about twenty minutes. This once-a-week exercise along with everyday cold showers will help you to get rid of acne.

Purification of the skin at Hippocrates is a multi faceted approach to treat acne inside out. This approach for acne  prevention involves a clear skin diet, a skin care and attention to overall hygiene and lifestyle. Please note that severe acne condition should be consulted and treated by a physician or healthcare provider. The main reason is that the treatment must be tailored for the affected individual. It is worth reminding, prevention and paying attention to acne life style modifications in primary stages of acne in an adult or adolescent can prevent scars, which are more difficult to treat.

Clear skin diet and nutrition considerations to rid acne vulgaris more effectively,

Clear Skin Lifestyle and Prevention Protocol: The Holistic Hippocrates Approach

Even though a direct relationship between acne and diet was denied by many studies in the past and for long time role of diet was considered one of acne myths, more recent research indicate exacerbation of acne by hyperglycemic diet and high intake of milk products. Importance of diet in prevention and maintenance treatment of acne patients has gained substantial consideration in our guidelines.

By large, these studies suggest upregulation of insuling, insulin-like-growth-factor (IGF-1) and over-activation of m-TORC1 by high glycemic index diets, which, in turn increase androgens and sebocytes lipogenesis. Specific foods that cause acne has not been identified, however, certain diet considerations may help body immune system, promote a hormonal balance and as a result alleviate acne and sebum production. Several studies suggest certain diets and plants may influence congestion of intestinal bacteria, impact gut-skin axis and implicate in pathogenesis of acne.

1. Start a diet high in fiber and foods with lower glycemic index such as Salads, whole wheat bread, bran or multi grain to keep your digestive system moving fast and not burdening it with handling wastes and in general eating whole grains and whole food as opposed to highly processed food.

2. Eat plenty of different fruits everyday, carrots, apples, berries, grapefruit, orange, and cantaloupes… High content of anti oxidants in diet help your body to rid inflammatory acne

3. Drink 8 glasses of water every day. Water help your skin rid toxins and the transport of nutrients to your skin

4. Unlike what you may think, nuts are good for acne prone skin. Nuts are rich in gamma linolenic acid and certain linoleates which may involve in treatment of acne. These essential fatty acids deficiency contributes to sebaceous gland hypertrophy and hyperkeratinization of the ducts

5. Avoid meats high in animal fat, salami, pepperoni, meatballs with a questionable association with hormonal acne

6. Consider moderate use of sweets in your clear skin diet, chocolate bars, candies, different drinks high in sugars as a teenager and lower use of them as you grow up. Honey is an excellent replacement for sugars. Low glycemic diets are warranted in control and management of acne vulgaris.

7. Food allergies may contribute to adult blemishes and delay treatment. If you are experiencing aggravation of your acne with certain food, eliminate it from your clear skin diet

8. Overall a diet low in saturated fats (animal fats) and sugar can strengthen your immune system which, in turn, help your skin’s defense mechanisms and aid your treatment of acne. It is worth remembering nuts including pistachio, almonds, peanut, cashews, walnut are not only great for your skin due to their high content of linolenic acid but they help stabilize your blood sugar level, prevent abrupt hormone fluctuations as well as anti bacterial activity of omega-3 fatty acids against propionibacterium acnes

9. Foods high in bioflavanoids and alpha lipoic acid could be helpful because of its contribution to rid free radicals. Liver and Brewer’s yeast are sources of alpha lipoic acid. Drink plenty of Green tea as it is a good antioxidant high in polyphenols

10- More recent studies suggest oral intake of omega 3 fatty acids to ameliorate acne lesions and is associated with improved outcomes as adjunct treatment

Life style modifications to treat and manage acne vulgaris equally implicates hygiene tips and precautions

1. Wash your face with a gentle pH balanced cleanser twice a day, once before you going to bed and once in the morning. Soaps and many cleansers in the market have alkaloid pH, which is not consistent with acid mantle of the skin. These cleansers tend to stimulate sebaceous glands to produce more sebum. The result is more oily skin. Cleansing is of crucial importance in any acne treatment dermatologist regimen whose main target is for comedonal acne prevention such as blackheads and whiteheads

2. Do not use any type of soap to wash your face, the alkaline pH of soaps stimulate production of sebum. Increased sebum production is involved in development of adult blemishes

3. Use a treatment at night over cleansed dry skin before going to bed such as acne serum

4. Use a moisturizer for acne prone skin type during the day over cleansed skin. Keeping your skin moist during the day is important for microcomedones and acne prevention and excess production of sebum

5. Do not touch or rub your face and anywhere else you have acne on

6. Daily showers prevent accumulation of excess sebum on the skin and could be a rewarding adjunct to your clear skin diet. Once-a-week a hot bath is of great help in elimination of toxins and excess sebum. Wash your body with a body wash or a pH balanced shampoo rather than a soap. Wash your towels more frequently.

7. Wash armpits and genital areas separately while taking shower. These areas are where bacteria especially Staphylococcus reside more readily

8. Very important point: Do not let your face touch the pillow while you sleep, the mechanical stimulation can cause blemishes, especially if you are experiencing acne on sides of your face for long time. Sufficient sleep does substantiate in health of the skin and maintenance treatment of acne vulgaris.

9. After exercise showers. If you work out make sure you take a shower right after. Do not postpone your shower. The longer you postpone it, the more likely development of comedones, blackheads, whiteheads. Your sweatened skin is a more desirable environment for opportunistic bacteria.

10. Expose yourself to sunlight and fresh air 30 minutes every day. Wear a sunscreen and do not be scared of sun rays. This 30 minutes exposure is stimulating as well as balancing for your endocrine system.

Lifestyle-Based Acne Prevention: Natural Strategies to Prevent Acne Vulgaris and Promote Clear Skin

Adequate sleep for hormonal balance and acne prevention is increasingly recognized as a cornerstone of dermatologic health. Deep, restorative sleep—ideally 7–9 hours per night—facilitates the secretion of growth hormone, which supports tissue repair, nutrient absorption, and skin regeneration. Importantly, insufficient sleep contributes to hormonal dysregulation, notably an increase in cortisol and androgens, which are implicated in sebaceous gland hyperactivity and subsequent acne flare-ups.

Sleep also modulates the immune system’s efficacy in combating acne-causing bacteria, such as Cutibacterium acnes. Melatonin, another sleep-associated hormone, exerts antioxidant, antiviral, and immunomodulatory effects, further supporting its role in natural acne prevention strategies.

Recent evidence challenges the long-standing belief that diet has negligible impact on acne. Contemporary research highlights the significance of the gut-skin axis, systemic inflammation, and insulin-like growth factor 1 (IGF-1) in the pathophysiology of acne vulgaris.

Dietary guidelines for preventing acne naturally include:

  1. Low glycemic index diet: Whole grains, legumes, and vegetables reduce IGF-1 signaling, mTORC1 activation, and androgen-driven sebum production.
  2. Antioxidant-rich fruits: Daily intake of berries, citrus fruits, and carrots enhances free radical scavenging and reduces inflammatory acne lesions.
  3. Adequate hydration: Eight glasses of water per day support lymphatic clearance and toxin elimination from the skin.
  4. Essential fatty acids: Nuts and seeds rich in gamma-linolenic acid help restore skin barrier integrity and may downregulate sebocyte activity.
  5. Moderation in dairy and sugar: Reduced consumption of high-fat dairy and refined sugar helps in hormonal acne prevention, particularly in adults.
  6. Nutraceuticals and supplements: Oral omega-3 fatty acids, alpha-lipoic acid, and polyphenols from green tea have shown adjunctive efficacy in improving acne severity.

Regular physical activity plays a dual role in acne prevention: enhancing circulatory efficiency and detoxification, while also modulating endocrine balance. Aerobic exercise, practiced for at least 30 minutes three times weekly, reduces systemic cortisol and promotes hormonal homeostasis, especially relevant for individuals with androgen-mediated acne.

Incorporation of mindfulness practices

Mind-body techniques such as yoga, tai chi, and meditative relaxation can enhance microcirculation, decrease stress-induced inflammation, and aid in balancing sebum production.

Natural Acne Prevention Skincare and Cleansing Practices

Foundational acne-preventing skincare routines consist of:

  1. Gentle, pH-balanced cleanser: Avoid alkaline soaps, which disrupt the skin barrier and stimulate sebum production. Natural alternatives such as white vinegar as a natural acne cleanser may offer antimicrobial benefits.
  2. Moisturizer with essential fatty acids: Hydration is essential, even for oily skin. Oil-free formulations may aggravate lipid imbalances in acne-prone individuals.
  3. Targeted antioxidant treatment: Application of serums enriched with vitamin C, niacinamide, or plant-based antioxidants helps in managing inflammatory acne lesions.

Steam treatments using chamomile infusion once weekly may offer pore-decongesting and anti-inflammatory effects, but should be avoided more frequently to prevent barrier compromise.

Bathing Habits, Personal Hygiene, and Acne Prevention

Hygiene practices are fundamental to acne management and prevention. Key recommendations include:

  • Daily lukewarm showers for oily skin control using pH-balanced cleansers or body washes.
  • Weekly therapeutic baths with Epsom or sea salts can assist in toxin elimination and sebaceous regulation.
  • Avoid mechanical stimulation of acne-prone skin through abrasive cloths or excessive face-touching.
  • Post-exercise showers prevent sweat-induced bacterial proliferation and comedone formation.
  • Changing pillowcases and towels frequently minimizes skin exposure to Staphylococcus species and environmental debris.

The Hippocrates method for acne prevention integrates nutrition, skincare, lifestyle modifications, and hygiene protocols to address both internal and external acne triggers. This multifaceted strategy emphasizes the interdependence of the endocrine system, immune function, gut health, and skin microbiome affected by prolonged antibiotics use.

The goal of lifestyle modification for acne is not merely to treat symptoms, but to prevent long-term sequelae such as scarring and pigmentation by intervening early and consistently.

Summary and Clinical Perspective

A comprehensive lifestyle-focused acne prevention regimen—grounded in evidence-based practices—can significantly improve the prognosis of acne vulgaris, particularly in adolescents and young adults. Dietary adjustments, stress reduction, consistent skincare, and sleep hygiene work synergistically to reduce sebaceous gland activity, modulate inflammatory cytokine production, and support immune surveillance of cutaneous pathogens.

For individuals with persistent or severe acne, professional dermatologic consultation remains essential to rule out underlying endocrine disorders, such as polycystic ovarian syndrome, or to escalate treatment toward pharmacologic modalities.